Do spermicide condoms work? Pros and cons Lube and fertility: Can lube impact your chances of conceiving? Does the Lubricant in Condoms Cause Harm? Vinmec Condoms protect against unplanned pregnancy and most sexually transmitted infections, including HIV, gonorrhoea, chlamydia, and syphilis. Use only water or silicone based lubricant with a condom during vaginal and particularly anal sex The difference between spermicidal and non spermicidal condoms Study finds PFAS in condoms and lube, prompting concerns about sperm and overall health