Let's talk about lubricants and fertility. If you're TTC, the type of lube you use can either support or sabotage your chances of conceiving. Here's what research shows: All impact sperm in Can your lube affect your chances of getting pregnant? Yes some lubricants can make it harder for sperm to reach the egg. Look for sperm safe or fertility friendly formulas that mimic your Conceive Plus Fertility Lubricant, Fertility Personal Lubricant Formula for Couples Trying to Conceive, Multi Use Tube 2.5 fl.oz. HSA FSA Eligible Walmart.com Fertility Lubricant: Safe Use When Trying to Conceive Gamete, Fertilization and Embryo Compatible Lubricants: The New FDA Product Code PEB Updates the Standard of Care for Trying to Conceive Couples SciTechnol Do Lubricants Affect Pregnancy Chances? Many couples wonder if lubricants can prevent conception. Oil based lubricants (like Vaseline, coconut oil, creams, lotions) can slow down sperm movement and reduce pregnancy chances.