Do Lubricants Affect Pregnancy Chances? Many couples wonder if lubricants can prevent conception. Oil based lubricants (like Vaseline, coconut oil, creams, lotions) can slow down sperm movement and reduce pregnancy chances. JO Actively Trying Fertility Friendly Lubricant, Water Based Lube for Women & Couples Trying to Conceive, 4 Oz Walmart.com B Arm Fertility Friendly Lubricant for Couples Trying to Conceive 50ml 100% Natural, Glycerine free, pH Balanced & Water Based Lubricant Fragrance free & Non Sticky Sperm Friendly Lube for Men & Women B Arm Medical Can your lube affect your chances of getting pregnant? Yes some lubricants can make it harder for sperm to reach the egg. Look for sperm safe or fertility friendly formulas that mimic your Did you know: most lubricants (and yes, saliva) can harm sperm motility, exactly the opposite of what you want when youre trying to grow your family. Our Power Play Lube was created to help your Actively Trying Fertility Lubricant